MU Ning, GAO Wanrong, ZHOU Yawen, “Non-invasive Observation of Human Tissue Samples with Full Field Optical Coherence Tomography,” Chinese Journal of Electronics, vol. 28, no. 5, pp. 987-992, 2019, doi: 10.1049/cje.2019.06.018
Citation: MU Ning, GAO Wanrong, ZHOU Yawen, “Non-invasive Observation of Human Tissue Samples with Full Field Optical Coherence Tomography,” Chinese Journal of Electronics, vol. 28, no. 5, pp. 987-992, 2019, doi: 10.1049/cje.2019.06.018

Non-invasive Observation of Human Tissue Samples with Full Field Optical Coherence Tomography

doi: 10.1049/cje.2019.06.018
Funds:  This work is supported by the National Natural Science Foundation of China (No.61275198, No.60978069) and the Key Special Projects of "Major Scientific Instruments and Equipment Development" of the National Key Research and Development Plan, Ministry of Science and Technology, P. R. China (No.2017YFF0107100).
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  • Corresponding author: GAO Wanrong (corresponding author) received the Ph.D.degree from Xi'an lnstitute of Optics and Fine Mechanics,Chinese Academy of Science in 1996.He is a professor in the Department of Optical Engineering,Nanjing University of Science and Technology.His research interests include biomedical optics and spectroscopy.(Email:wgao@njust.edu.cn)
  • Received Date: 2019-04-10
  • Rev Recd Date: 2019-06-03
  • Publish Date: 2019-09-10
  • In this work, we report on non-invasive observation of human esophagus, liver, and uterus samples with Full field optical coherence tomography (FFOCT). ln imaging process, fresh human samples were fixed in formalin immediately after excision and then imaged directly without staining and cutting the samples into a serial of thin slices. Tissue microstructures of each type of normal or cancerous tissue as well as their changes with the increase of the depth beneath tissue surface can be identified in the depth-resolved images. The results demonstrate the potential of applications of the en face images in clinic practice.
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