A study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR

DU Yuxiao; LI Gaoming

doi:10.23919/cje.2023.00.213

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Article Navigation > Chinese Journal of Electronics > 2024 > Accepted Manuscript

Yuxiao DU and Gaoming LI, “A study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR,” Chinese Journal of Electronics, vol. x, no. x, pp. 1–12, xxxx doi: 10.23919/cje.2023.00.213

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Yuxiao DU and Gaoming LI, “A study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR,” Chinese Journal of Electronics, vol. x, no. x, pp. 1–12, xxxx doi: 10.23919/cje.2023.00.213

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A study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR

doi: 10.23919/cje.2023.00.213

DU Yuxiao,
LI Gaoming^,

1.
School of Automation, Guangdong University of Technology, Guangzhou 510006, China

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Author Bio:
Yuxiao DU was born in 1973. He received the Ph.D. degree in School of Information Science and Engineering, Central South University, Changsha, China, in 2004. He is an Associate Pro fessor of School of Automation, Guang dong University of Technology. His re search interests include intelligent manu facturing and industrial robot techno logy and brain computer interface technology. (Email: yuxiaodu@gdut.edu.cn)

Gaoming LI was born in 1996. He received the B.E. degree in automation, Zhengzhou University, Zhengzhou, China, in 2020. He is currently pursing the M.E. degree in con trol science and engineering from Guang dong University of Technology, Guang zhou, China. His research interests in epilepsy EEG processing. (Email: qq1334676416@163.com)
Corresponding author: Email: qq1334676416@163.com
Available Online: 2024-04-01

Abstract

Abstract

Studies have shown that fast ripples of 250-500 HZ in epileptic EEG signals are more pathological and closer to the epileptogenic focus itself compared to ripples of 80-250 HZ. However, artifacts of fast ripples and HFOs are easily confused and difficult to discriminate, and manual visual screening is both time-consuming and unable to avoid subjectivity. To this end, this paper presents a method for localizing epileptogenic foci based on the automatic detection of integrated feature HFOs and RF-LR. In this paper, we first extract multivariate features from the preprocessed epileptic EEG signals, and use the random forest algorithm to filter out three features with high importance, based on which, suspicious leads containing HFOs are identified. Then, wavelet time-frequency maps were used for the primary screening of suspected leads to improve the signal calibration efficiency and further localize HFOs in time and frequency. Finally, a logistic regression model was used to automatically classify and identify ripples and fast ripples in HFOs. The results show that the sensitivity, specificity, and accuracy of the model for detecting ripple are 89.37%, 88.26% and 90.1%, respectively; the sensitivity, specificity, and accuracy for detecting fast ripple are 94.31%, 94.83% and 93.46%, respectively. Compared with single features, the multivariate features in this paper more comprehensively characterize the complex epileptic EEG signals and provide more accurate information for the localization of epileptogenic foci. The automatic detection algorithm of HFOs proposed in this paper can analyze a large amount of data in a short time and has a good detection performance, which can help clinicians accurately determine the region of epileptogenic foci.
- high-frequency oscillation,
- multivariate features,
- random forest,
- logistic regression

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References(37)

References

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