To realize intelligent and comprehensive fa- cial expression generation of virtual agent, a novel model of layered fuzzy facial expression generation is proposed. In this model, social, emotional and physiological lay- ers contribute to the fuzzy facial expression generation. Then, a layered fuzzy facial expression generation system is founded, where in°uences of the three layers and ex- pression personality are considered for intelligent decision of facial expression generation based on fuzzy theory. A novel layered fuzzy facial expression generation language is also developed for conveniently controlling facial expres- sion generation of virtual agent. The system is evaluated by subjects and compared with other systems, showing that it is e±cient for intelligent facial expression gener- ation of virtual agent.